Child and Adolescent Psychiatry

Research

LUCINA UDDIN:

http://med.stanford.edu/profiles/Lucina_Uddin/

The overarching goal of my research program is to understand the organization and development of neurocognitive networks that give rise to cognition and behavior. To this end, I have developed a three-pronged research program to study a) functional and structural connectivity of large-scale brain networks in healthy adults, b) the maturation of functional and structural connectivity in typical development, and c) the cognitive and behavioral consequences of atypical development of these systems. My research capitalizes on recent methodological advances in functional magnetic resonance imaging (fMRI) and diffusion tensor imaging (DTI) to examine brain connectivity underlying both typical and atypical cognition. Current projects examine functional and structural brain connectivity and its relationship to cognitive function in the healthy adult brain, with extensions to typical development and relevant neurodevelopmental disorders of connectivity including autism spectrum disorders (ASD). I have applied this multimodal, connectivity-based neuroimaging approach in the domains of attention and social cognition, however my work has widespread implications for the study of memory, language, and cognitive control.


DR. VICTOR CARRION:

http://elsrp.stanford.edu/
The Stanford Early Life Stress Research Program is part of the Department of Psychiatry and Behavioral Sciences in the Division of Child and Adolescent Psychiatry at Stanford University. The lab seeks to better understand the cognitive, behavioral and biological correlates of childhood stress and trauma. We seek to promote resiliency in children who have been through adverse events and to develop enhanced individual and commnunity interventions.
Our lab is located on the third floor of the Psychiatry Building at 401 Quarry Road, Room 3343 on the campus of Stanford University.
Contact Information:
Stanford Early Life Stress Research Program
Stanford University School of Medicine
Psychiatry and Behavioral Sciences
401 Quarry Road
Room 3343
Stanford, CA 94305
Telephone: 650-724-3377



 DR. KIKI CHANG:
The Stanford Pediatric Bipolar Disorders Program serves to study the cause, presentation, and treatment of bipolar disorder (BD) in children and adolescents. Our central mission is to understand which children are at risk for developing BD so that we can intervene to prevent the disorder. In order to do this, we are conducting studies designed to discover brain and gene abnormalities that are unique to early-onset BD.  Together with early symptoms, these biological "markers" could then be used to predict the amount of risk that children have for developing full-blown BD.  These markers would also provide information on the cause of BD, enabling better treatments to be developed. As BD is a chronic disorder that affects millions of children, who largely then become adults with BD, we feel it is necessary to focus our efforts on the early identification and prevention of this disorder.  Please see our Research page for more information on our current studies, and contact us at (650) 725-6760 or by email if you are interested in joining our research.


DR. MANPREET SINGH:
Manpreet K. Singh, MD MS
Assistant Professor of Child and Adolescent Psychiatry and Child Development, and Co-director of the Pediatric Mood Disorders Clinic Department of Psychiatry and Behavioral Sciences Stanford University School of Medicine Stanford, CA

Dr. Singh combines advanced research methods such as neuroimaging, genetic analyses and neurobehavioral assessment to examine how genetic and environmental factors affect brain structure and function, and how this ultimately impacts the development and function of youth with a spectrum of mood disorders, including unipolar depression and bipolar disorder. An important focus of this work is identifying gene-brain-behavior interactions relevant to the development of more specific and effective interventions. Another focus is on the neuroscience of resilience in typically developing persons including studies of the brain basis of motivation, stress responsivity, and emotion regulation.  Dr. Singh has received numerous grants from Stanford, from the National Institute of Health (NIH), and from private foundations.  She currently serves as a principal investigator on an NIH-funded project examining factors associated with resilience and risk for developing bipolar disorder in childhood. Notable awards and honors received include the NIH Loan Repayment Program, the NARSAD Young Investigator Award, the Klingenstein Third Generation Foundation Depression Fellowship, and the American Psychiatric Association’s Young Minds in Psychiatry International Award. Dr. Singh mentors undergraduate and graduate students, as well as post-doctoral fellows to encourage growth of her chosen field.  For additional information about the Pediatric Bipolar Disorders Program, please see the following link:
http://pediatricbipolar.stanford.edu/


DR. HANS STEINER:
Dr. Steiner's predominant interest is the application of Humanistic principles to the practice of Medicine and Psychiatry.

He is a founding member of the PEGASUS PHYSICIANS at Stanford, a working group of Stanford physicians who write creatively. The group meets monthly and discusses writing proposals, poetry, novels and trade books in progress. Members of the group have an extensive publication record. The group meets monthly on Tuesday evenings to discuss each others’ projects. The group is open to practicing physicians who write, including medical students. We usually ask prospective members to send a writing sample of undetermined length.  The group can be reached by e mailing Dr. Steiner at Stanford or via his private website at: www.hanssteiner.com.

Dr. Steiner's research is based on developmental approaches to psychopathology which emphasize the conjoint study of normative and non-normative phenomena, and the complex interaction of biological, psychological and social variables in the etiology, pathogenesis, diagnosis and treatment of mental disorders. These principles are amply evident in his latest Handbook of Developmental Psychiatry published by World Scientific and Imperial College Press (2011)He has published extensively on the details of this model and has applied it to the study of normal and abnormal aggression, responses to stress and traumatic events, and the mental processes helping people adjust to adversity across the life span. He is currently investigating the application of psycholinguistic methods to measure conscious and unconscious mental states, especially emotions and self regulation. He is using computerized text analytic techniques to characterize referential activity, emotional expression, event specific memories and the reconstituting and healing effects of oral and written emotional expression. He is studying non-clinical and clinical populations with these methods. He is studying non-clinical adults and adolescents. He is studying clinical cohorts diagnosed with trauma related psychopathology, disruptive behavior and attention deficit, maladaptive aggression, eating disorders and other syndromes which present with complex combinations of psychosomatic and somato-psychic illness ( e.g. pain disorders, anxiety disorders, medical traumatization, somatization disorders etc.)


DR. WENDY FROEHLICH:
My clinical and research focus is centered on genetic syndromes associated with autism spectrum disorders, and using these syndromes to investigate the cellular and molecular basis of autism. I am involved primarily on the clinical end of the Autism Cellular Phenome Project led by Drs. Ricardo Dolmetsch and Joachim Hallmayer. This study involves creating induced pluripotent stem cells, and subsequently neurons, from skin samples provided by children with autism associated genetic syndromes. In addition, the Stanford EKG and autism study is collecting electrocardiograms in children with autism spectrum disorders to help understand whether there may be underlying genetic disorders affecting pathways involved in both the brain and the heart.


DR. VINOD MENON:
Vinod Menon, Ph.D.
Professor of Child and Adolescent Psychiatry & Child Development, Professor of Neurology & Neurological Sciences, and Professor of Neuroscience
Director, Stanford Cognitive & Systems Neuroscience Lab 
Stanford University School of Medicine Stanford, CA

Dr. Menon (http://med.stanford.edu/profiles/Vinod_Menon) is Director and Principal Investigator of the Stanford Cognitive and Systems Neuroscience Laboratory, a multidisciplinary brain research group in the Department of Psychiatry and Behavioral Sciences at the Stanford University School of Medicine. Our goals are to (1) discover fundamental principles underlying normal brain and cognitive development, (2) develop brain-based evidence and interventions to improve cognitive skills in children with learning disabilities, and (3) investigate atypical development of cognitive, affective and social information processing systems in children with autism. We use advanced brain imaging techniques (fMRI, sMRI, DTI and EEG) as well as behavioral, genetic and computational methods in our research. Populations currently under investigation include normal healthy children, adolescents and adults, children with learning disabilities and children with autism. For additional details about our lab and research please see: http://scsnl.stanford.edu.


DR. LAUREN MIKULA-SCHNEIDER:
My primary research interests are in the area of pediatric psychology and involve adjustment and coping to pediatric illness and adherence to medical regimens.  I am collaborating with colleagues on a multisite study sponsored by The National Institute of Allergy and Infectious Diseases: Clinical Trials in Organ Transplantation in Children, CTOTC-05. The study is examining perceived barriers to patient adherence after pediatric solid organ transplantation.  Additionally, I am collaborating with colleagues on a multisite prospective epidemiological study of children with chronic kidney disease, which is sponsored by The Division of Kidney, Urologic, and Hematologic Diseases (DKUHD) of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), the National Institute of Neurological Disorders and Stroke (NINDS), the National Institute of Child Health and Human Development (NICHD) and the National Heart, Lung and Blood Institute (NHLBI). Specifically, I will be contributing to one of the goals of the study that relates to defining how a progressive decline in kidney function impacts neurocognitive function and behavior. 


 

DR. RICHARD SHAW:

http://med.stanford.edu/profiles/Richard_Shaw/

Richard Shaw, M.D.
Professor of Psychiatry and Pediatrics
Division of Child Psychiatry
Stanford University School of Medicine

Dr. Shaw’s primary area of research is related to the psychological issues affecting children with complex and chronic physical illness.  One major topic is that of posttraumatic stress reactions in children and family members who are receiving treatment in the hospital setting.  Dr. Shaw is currently conducting an NIMH-funded R-34 grant developed to help prevent or reduce symptoms of posttraumatic stress in mothers who have infants hospitalized in the neonatal intensive care unit.  This study integrates principles of Trauma-focused CBT with interventions to enhance parenting skills in mothers of preterm infants.  Dr. Shaw is also involved in research on PTSD in patients with acute respiratory distress admitted to intensive care units.  A second focus of Dr. Shaw’s research is in the field of transplant psychiatry.  He has conducted studies on the issue of adherence to medical treatment regimens in adolescent solid organ transplant recipients as well as on potential methods of screening organ transplant recipients prior to transplant. 


 

DR. JENNIFER PHILLIPS:

Dr. Phillips is a clinical associate professor in the child psychiatry clinic. Her clinical interests include developmental and neuropsychological assessment of children and adolescents with developmental, learning, and autism spectrum disorders.  She is also interested in parent consultation services for addressing behavioral issues and building skills in the home.  She teaches a parent education class for parents of young children with autism spectrum disorders throughout the year.  Dr. Phillips is also extensively involved in a variety of research projects focused on children with autism, including projects related to efficacy of behavioral treatments, and understanding neurodevelopmental differences in children with autism.  She leads a research team which provides diagnostic and cognitive testing for children enrolled in many autism research projects at Stanford.  Dr. Phillips is a faculty member in the Stanford-PGSP PsyD Consortium, which is a Clinical Psychology graduate training program. Her role in this program is to coordinate a child emphasis for students, as well as to advise, supervise, and teach students interested in child psychology.

Relevant websites:
http://autism.lpch.org
http://autismdd.stanford.edu
www.paloaltou.edu


 

DR. SHARON WILLIAMS:

Dr. Williams' work focuses primarily on cognitive and emotional recovery of children who have been medically compromised. With improved medical treatment and increased survival rates comes the need to better understand the challenges that patients face following a life threatening illness or injury. Advances in medical technology have opened the door to a better understanding of cognitive development and the recovery or deterioration process over time. Currently, Dr. Williams is examining the neuropsychological impact of treatment for children who have undergone a hematopoietic stem cell transplant (HSCT). The existence of cognitive deficits in this population - intellectual and academic functioning, memory impairment, visual motor difficulties, problems with attention, concentration and executive functioning - has been in question over the years with research supporting both perspectives. Dr. Williams' work will help to illuminate this issue and provide direction for families whose children undergo this procedure.  Additionally, Dr. Williams has studied the recovery process of children with traumatic brain injuries and continues to see these children in her clinical practice.


DR. KARI BERQUIST, BCBA-D:

Dr. Berquist is a clinical instructor in the child psychiatry clinic. She divides her time between clinical and research work. Her main clinical interests include behavioral intervention for children and adolescents diagnosed with autism spectrum disorder and related disorders. She also focuses her clinical work on teaching parents of children with autism and developmental delays how to facilitate behavioral change in the home, school, and community settings. Her behavioral treatment is rooted in developmental theory and naturalistic teaching strategies based on the principles of applied behavior analysis.  She addresses behavioral issues related to: communication, social skills, restricted, repetitive, and stereotyped behaviors, anxiety, feeding, non-compliance, and independent living skills. For more information on clinical services please see http://autism.lpch.org .In addition to her clinical work, Dr. Berquist is currently involved in various research projects through the autism and developmental disabilities research lab. She is involved in many clinically based studies in which she teaches parents of children with autism spectrum disorder the skills to implement Pivotal Response Training and to evaluate the effectiveness of autism interventions.  Many of these studies and enrollment can be viewed at http://autismdd.stanford.edu

 


DR. MARY SANDERS


DR. SHASHANK JOSHI

Dr. Joshi's teaching and research focuses on increasing knowledge and enhancing effectiveness of school mental health, pediatric psychotherapy and medication interventions. Areas of study include: the therapeutic alliance in medical care, structured psychotherapy interventions in school settings, and the teaching of pediatric psychopharmacology to medical students, residents, and fellows.

 


DR. KRISTA FIELDING


DR. ANTONIO HARDAN

The neurobiology of autism Neuroimaging in individuals with autism Psychopharmacological treatment of children with autism and/or intellectual disabilities Neurobiology and psychopharmacology of schizophrenia and early onset psychotic disorders

 


DR. JAMES LOCK
http://edresearch.stanford.edu./


DR. JOACHIM HALLMAYER:
Dr Hallmayer has been involved in research on autism for over 20 years. The focus of his laboratory is to find genes predisposing to autism and to resolve the heterogeneity of clinical phenotypes into genetically simpler, quantifiable components, thus facilitating the search for susceptibility genes. His work encompasses the recruitment, the laboratory, and the analytic side. He and his collaoborators had conducted several genome wide linkage and association studies. These studies have identified multiple rare mutations in children with autism. It is estimated that approximately 15% to 20% of individuals with ASD have an identifiable genetic. Dr Hallmayer has also been the PI of the largest population-based, sociodemographically diverse twin study that used contemporary standards to diagnose autism. Results from this study suggest that the heritability of autism has been previously overestimated and that environmental factors play a significant role in the etiology of autism.
In collaboration with Dr Dolmetsch he has initiated studies of induced pluripotent stem cells derived from individuals with autism. In the initial phase our focus is on children diagnosed with autism with a known genetic mutation. The plan is to expand these studies to include children with autism of unknown etiology.
Dr Hallmayer is the Chair of the Committee of Senior Investigators of the largest collaborative research project on autism, the Autism Genome Project, with over 100 researchers from 50 centers in North America, Europe, and Asia. He is also the Chair of the Executive committee of the Bay Area Autism Consortium, a consortium of academic institutions and service providers interested in fostering research on autism.

Dr Hallmayer earned his MD and his Dr med from the University of Cologne. He was as postdoctoral fellow in the laboratory of Dr Cavalli-Sforza at Stanford University. He then became a faculty member in the Department of Psychiatry at the University of Western Australia. In 2001 he moved to Stanford University.


DR. SANNO ZACK:


DRS. GRACE GENGOUX, MINA FISHER, MICHELLE BROWN


DR. MEGAN JONES


NINA KIRZ

LAUREN MIKULA-SCHNEIDER
JENNIFER PHILLIPS
SHARON WILLIAMS
KARI BERQUIST
MARY SANDERS
SHASHANK JOSHI
KRISTA FIELDING
ANTONIO HARDAN
JOACHIM HALLMAYER
SANNO ZACK
GRACE GENGOUX
MINA FISHER
MICHELLE BROWN
MEGAN JONES
NINA KIRZ

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